Novel approaches in myelofibrosis
Posted: Fri Dec 20, 2024 4:57 pm
I stumbled across this comprehensive and recent (12 Dec 24) list of ongoing clinical trials for patients with myelofibrosis. It may be of value to anybody interested in what's out there in the (near) future.
https://onlinelibrary.wiley.com/doi/ful ... m4b_IpWYWw
Also, just because I heard about it at the same time, here is a brief summary of a very interesting trial of a new drug PXS-5505 in addition to current Ruxo dose.
(Apologies for the Twitter / X link - it's all I have. If you want the slides as images let me know and I'll attach them here).
https://x.com/MPN_Hub/status/1866438731 ... 79/photo/1
In summary: 9 out of 11 patients had a stable or reduced spleen volume. PXS-5505 is safe and well tolerated. Reductions in spleen volume and symptoms continue to improve over time.
https://onlinelibrary.wiley.com/doi/ful ... m4b_IpWYWw
Also, just because I heard about it at the same time, here is a brief summary of a very interesting trial of a new drug PXS-5505 in addition to current Ruxo dose.
(Apologies for the Twitter / X link - it's all I have. If you want the slides as images let me know and I'll attach them here).
https://x.com/MPN_Hub/status/1866438731 ... 79/photo/1
In summary: 9 out of 11 patients had a stable or reduced spleen volume. PXS-5505 is safe and well tolerated. Reductions in spleen volume and symptoms continue to improve over time.
