I stumbled across this comprehensive and recent (12 Dec 24) list of ongoing clinical trials for patients with myelofibrosis. It may be of value to anybody interested in what's out there in the (near) future.
https://onlinelibrary.wiley.com/doi/ful ... m4b_IpWYWw
Also, just because I heard about it at the same time, here is a brief summary of a very interesting trial of a new drug PXS-5505 in addition to current Ruxo dose.
(Apologies for the Twitter / X link - it's all I have. If you want the slides as images let me know and I'll attach them here).
https://x.com/MPN_Hub/status/1866438731 ... 79/photo/1
In summary: 9 out of 11 patients had a stable or reduced spleen volume. PXS-5505 is safe and well tolerated. Reductions in spleen volume and symptoms continue to improve over time.
Novel approaches in myelofibrosis
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Re: Novel approaches in myelofibrosis
Thanks so much again Pete for Posting... 
I love diving into research as often as time permits, I shall be sure to take a deeper dive shortly...
Best wishes
Steve
PS. Pete, pls don't forget to "Subscribe" to the FORUM, so that you are always notified of any responses etc...
If you scroll down on your own Post (Editing). You'll also notice a radio box to be 'Ticked" – Notify me when a reply is posted

I love diving into research as often as time permits, I shall be sure to take a deeper dive shortly...
Best wishes
Steve
PS. Pete, pls don't forget to "Subscribe" to the FORUM, so that you are always notified of any responses etc...

If you scroll down on your own Post (Editing). You'll also notice a radio box to be 'Ticked" – Notify me when a reply is posted